zhuhai Tianhui Chemical Co.,Ltd.
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Home>Products>Weight Loss Steroids>99% Purity Raw Prohormones Steroids Powder Misoprostol CAS 59122-46-2

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  • 99% Purity Raw Prohormones Steroids Powder Misoprostol CAS 59122-46-2
  • 99% Purity Raw Prohormones Steroids Powder Misoprostol CAS 59122-46-2

99% Purity Raw Prohormones Steroids Powder Misoprostol CAS 59122-46-2

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zhuhai Tianhui Chemical Co.,Ltd.

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  • zhuhai Tianhui Chemical Co.,Ltd.2020-07-10 09:46:19
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Product Details

Name: Misoprostol CAS: 59122-46-2 Assay: 99%
Apearance: White powder

Product Description

99% Purity Raw Prohormones Steroids Powder Misoprostol CAS 59122-46-2

 

Quick Detail:

Product name: Misoprostol
CAS:59122-46-2
Molecular Formula: C22H38O5
Molecular Weight: 382.60
Chemical Properties: White Solid
Assay:99%
Solubility: Soluble to 100 mM in Ethanol
Safety: Poison by ingestion, intramuscular, and intraperitoneal routes. When heated to decomposition it emits acrid smoke and irritating fumes.
Package: Aluminium foil bag packing
Storage: Keep in cool and dry place, away from light

 

Description:

Misoprostol is a medication used to start labor, induce abortions, prevent and treat stomach ulcers, and treat postpartum bleeding due to insufficient contraction of the uterus. For abortions it is used with mifepristone or methotrexate. It is a synthetic prostaglandin E1 (PGE1).

Common side effects include diarrhea and abdominal pain. It is pregnancy category X meaning that it is known to result in negative fetal outcomes if taken during pregnancy. Uterine rupture may occur.

It is on the World Health Organizations List of Essential Medicines, the most important medications needed in a basic health system. Misoprostol was invented and marketed by G.D. Searle & Company under the trade name Cytotec, but other trade names and generic formulations are available.

 

Application:

Misoprostol is approved for use in the prevention of NSAID-induced gastric ulcers. It acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell. Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors, are more effective for the treatment of acute peptic ulcers,

 

Specification:


Ref. Standard

According to enterprise internal control standard inspection

Results Of Analysis Tests

Test

Analysis Standard

Results

Description

Light Yellowish Crystalline Powder

Light Yellowish Crystalline Powder

Identification

(1)304nm,260nm.

confirmed

Melting Point

192°C~196°C

192°C~196°C

Specific Rotation

+124°~ +129°

+127.1°

(HPLC)
Related substances

(1)(Single):≤0.5%

0.31%
 
(2)(Total):≤1.0%

0.59%

Loss On Drying

≤0.5%

0.1%

Assay

≥98.5%

99.5%

Sieve analysis

≤30μm

confirmed

Conclusion

This product conforms to enterprise internal control standards
 

 

 

 

Usage:

Misoprostol is approved for use in the prevention of NSAID-induced gastric ulcers. It acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell. Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors, are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the elderly and people with ulcer complications. Misoprostol is sometimes coprescribed with NSAIDs to prevent their common adverse effect of gastric ulceration (e.g. with diclofenac in Arthrotec).

 

Misoprostol has other protective actions, but is only clinically effective at doses high enough to reduce gastric acid secretion. For instance, at lower doses, misoprostol may stimulate increased secretion of the protective mucus that lines the gastrointestinal tract and increase mucosal blood flow, thereby increasing mucosal integrity. However, these effects are not pronounced enough to warrant prescription of misoprostol at doses lower than those needed to achieve gastric acid suppression.

However, even in the treatment of NSAID-induced ulcers, omeprazole proved to be at least as effective as misoprostol,but was significantly better tolerated, so misoprostol should not be considered a first-line treatment. Misoprostol-induced diarrhea and the need for multiple daily doses (typically four) are the main issues impairing compliance with therapy.

 

The most commonly reported adverse effect of taking a misoprostol orally for the prevention of stomach ulcers is diarrhea. In clinical trials, an average 13% of patients reported diarrhea, which was dose-related and usually developed early in the course of therapy (after 13 days) and was usually self-limiting (often resolving within 8 days), but sometimes (in 2% of patients) required discontinuation of misoprostol.

The next most commonly reported adverse effects of taking misoprostol orally for the prevention of gastric ulcers are: abdominal pain, nausea, flatulence, headache, dyspepsia, vomiting, and constipation, but none of these adverse effects occurred significantly more often than when taking placebos. In practice, fever is almost universal when multiple doses are given every 4 to 6 hours.

 

Misoprostol should not be taken by pregnant women to reduce the risk of NSAID-induced gastric ulcers because it increases uterine tone and contractions in pregnancy, which may cause partial or complete abortions, and because its use in pregnancy has been associated with birth defects.

 

Our adwantage:
1, High quality with competitive price:
    1) Standard: Enterprise Standard
    2) All Purity≥98%
    3) We are manufacturer and can provide high quality products with factory price.

 

2, Fast and safe delivery
    1) Parcel can be sent out within 24 hours after payment. Tracking number available
    2) Secure and discreet shipment. Various transportation methods for your choice.
    3) Customs pass rate ≥99%
    4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

 

3, We have clients throughout the world.
    1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
    2) Market feedback and goods feedback will be appreciated, meeting customerss requirement is our responsibility.
    3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

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