99% Purity Colorless Liquid Gamma-Butyrolactone / GBL CAS 96-48-0

99% Purity Colorless Liquid Gamma-Butyrolactone / GBL CAS 96-48-0

 

Quick Detail:

Gamma-Butyrolactone

Alias: Gamma Butyrolactone, 1, 4- Butyrolactone, γ -Butyroladone, GBL, BLO

Purity : 99.9%

CAS Registry Number: 96-48-0

Einecs No: 202-509-5

MF: C4H6O2

MW: 86.09

Appearance: Colorless transparent liquid

Origin: China

Category: Flammable substance

Specification : Magic GBL with Magic effect

Usage: Gamma-butyrolactone is one kind of important fine chemicalintermediate, simultaneously also is one kind of performance fine highboiling point solvent, ideal antioxidant, plasticizer,extracting agent, absorbent, dispersing agent, solid stain, Coagulation Reagent.

 

Application:
Gamma-Butyrolactone is a hygroscopic colorless liquid with a weak characteristic odor which is soluble in water. is a common solvent and reagent in chemistry as well as being used as a flavouring, as a cleaning solvent, as a superglue remover, and as a solvent in some wet aluminium electrolytic capacitors. In humans it acts as a prodrug for, and it is used as a recreational intoxicant with effects similar to alcohol.

Gamma-Butyrolactone has been found in extracts from samples of unadulterated wines. This finding indicates that Gamma-Butyrolactone is a naturally occurring component in some wines and may be present in similar products. The concentration detected was approximately 5 μg/mL and was easily observed using a simple extraction technique followed by GC/MS analysis. Gamma-Butyrolactone can be found in cheese flavourings but typically results in a content of 0.0002% Gamma-Butyrolactone in the final foodstuff.

 

Under acidic conditions it forms an equilibrium mixture of both compounds. These compounds then may go on to form a polymer. When treated with a non-nucleophilic base, like lithium diisopropylamide, Gamma-Butyrolactone can become an alpha-carbon nucleophile. The related compound caprolactone can be used to make a polyester in this manner.

Gamma-Butyrolactone is not active in its own right; its mechanism of action stems from its identity as a prodrug of .

The hypnotic effect of is enhanced by combination with alcohol. A 2003 rat study showed that Gamma-Butyrolactone in combination with ethanol showed a potentiated hypnotic effect, as the sleep-timing measure was longer than both of the individual components combined.

 

Gamma-Butyrolactone is rapidly converted into by paraoxonase (lactonase) enzymes, found in the blood. Animals which lack these enzymes exhibit no effect from Gamma-Butyrolactone. Gamma-Butyrolactone is more lipophilic (fat soluble) than, and so is absorbed faster and has higher bioavailability. Because of these pharmacokinetic differences, Gamma-Butyrolactone tends to be more potent and faster-acting than, but has a shorter duration; whereas the related compound 1,4-butanediol (1,4-B) tends to be slightly less potent, slower to take effect but longer-acting than.

 

COA:

Items of analysis	Specification	Results
Appearance	Colorless transparent clear liquid.	Colorless transparent clear liquid
(wt%,GC) Purity	≥99.80	99.80
(wt%,K.F) Moisture	≤0.03	0.010
(Hazen) Color	≤20	6
(D20g/ml) Density	1.125-1.130	1.127
(Na20) Refractivity	1.436-1.437	1.4367
(wt%,GC)	≤0.02	0.018
(wt%,GC)	≤0.03	0.023
Conclusion	Qualified

 

Uses:

It is an important organic synthesis intermediate which can be used to synthesize indole butyric acid, butyric acid, succinic acid, α-pyrrolidone, N-methylpyrrolidone, vinyl pyrrolidone, acetyl-γ-butyrolactone, cyclopropylamine, ciprofloxacin, vitamin B1, chlorophyll and so on;
It is a non-toxic high boiling point solvent with high solubility and safe and convenient usage and management;
It is used as an extractant for butadiene, aromatic, advanced grease petroleum processing;
It is used as an acrylonitrile fiber spinning solvent in the chemical fiber industry.
It is a thinner and curing agent commonly used in wool, nylon, acrylonitrile and other fiber dyeing auxiliaries and other chemical industries.

 

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