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Home>Products>Raw Steroid Powders>NSI189 Raw Steroid Powders Nsi-189 Phosphate For Antidepressant CAS 1270138-41-4

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  • NSI189 Raw Steroid Powders Nsi-189 Phosphate For Antidepressant CAS 1270138-41-4
  • NSI189 Raw Steroid Powders Nsi-189 Phosphate For Antidepressant CAS 1270138-41-4

NSI189 Raw Steroid Powders Nsi-189 Phosphate For Antidepressant CAS 1270138-41-4

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  • zhuhai Tianhui Chemical Co.,Ltd.2020-07-10 09:46:19
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Product Details

Name: NSI-189 CAS No: 1270138-41-4 Assay: 99%
Appearance: White Powder

Product Description

NSI189 Raw Steroid Powders Nsi-189 Phosphate For Antidepressant CAS -41-4
 
Quick details :
Product Name: NSI-189
Other Name: [2-[(3-Methylbutyl)amino]-3-pyridinyl][4-(phenylmethyl)-1-piperazinyl]
CAS : -41-4
Purity: 99% min.
Molecular Formula: C22H30N4O
Molecular Weight: 366.50
Min order: 1g
Shipping: By Express DHL with tracking number provided
 
Describtion:
NSI-189 is a benzylphiperizine-aminiopyridine, nootropic and neurogenic research chemical created by Neuralstem, Inc. that was derived from pyrazine and nicotinamide. Studies have shown that it stimulates neurogenesis of human hippocampus-derived neural stem cells in vivo and vitro . In healthy adult mice, NSI-189 has been shown to increase the hippocampal volume by 20% and reverse behavioral symptoms in mouse depression models, meaning at the source it could address depression . The hippocampus is responsible for spatial navigation, along with the consolidation of information from short-term memory to long-term memory.
The chemical entity stimulates new neuron growth in the hippocampus, which is an area of the brain that is believed to be contributory in conditions such as post-traumatic stress disorder (PTSD), Alzheimers disease, and major depressive disorder (MDD).
 
COA:

Items of analysisSpecificationResults

Appearance

Off-white powder

Confrom

Identification

IR and HPLC spectrum shall conform to the standard sample

conform

Melting Point

83ºC~86ºC

84.3ºC~85.6ºC

Loss on Drying

Less than 0.5%

0.29%

Purity(On Dried Base,HPLC)

NLT 99.5 %

99.62%

Total Impurity

Less than 0.5%

0.33%

Residue On Ignition

≤0.2%

0.16%

Heavy metal

≤20ppm

conform
Conclusion

 
Qualified

 

 
Dosage:
Due to the fact that NSI-189 phosphate is still a trial drug, there has not yet been a fixed dosage. However, during the trials patients were given daily doses of 40mg, 80mg, and 120mg at the highest dose per day over the course of 28 days. During this period, patients did not report any serious events or side effects, and the NSI-189 phosphate was found to be well tolerated. Also, there was a significant reduction in depression and cognitive symptoms for patients taking the lower doses of 40mg and 80mg, but not for those taking 120mg per day. The preliminary findings of the trials are supportive of the idea that NSI-189 phosphate can treat MDD. Nonetheless, further studies on the dosage and the method of action of NSI-189 phosphate are imperative to help confirm preliminary observations and help draw conclusions.

 
Our adwantage:
1, High quality with competitive price:
    1) Standard: Enterprise Standard
    2) All Purity≥98%
    3) We are manufacturer and can provide high quality products with factory price.
 
2, Fast and safe delivery
    1) Parcel can be sent out within 24 hours after payment. Tracking number available
    2) Secure and discreet shipment. Various transportation methods for your choice.
    3) Customs pass rate ≥99%
    4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
 
3, We have clients throughout the world.
    1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
    2) Market feedback and goods feedback will be appreciated, meeting customerss requirement is our responsibility.
    3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
 
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