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Nsi189 Pharmaceutical Intermediate Raw Powder For Antidepressant 1270138-41-4
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zhuhai Tianhui Chemical Co.,Ltd.2020-07-10 09:46:19
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Product Details
Name: | Nsi-189 | Appearance: | white powder | purity: | 99% |
Product Description
Nsi189 Pharmaceutical Intermediate Raw Powder For Antidepressant -41-4
Name: | NSI-189 | CAS No: | -41-4 |
---|---|---|---|
Assay: | 99% | Appearance: | White Powder |
Quick details :
Product Name: NSI-189
Other Name: [2-[(3-Methylbutyl)amino]-3-pyridinyl][4-(phenylmethyl)-1-piperazinyl]
CAS : -41-4
Purity: 99% min.
Molecular Formula: C22H30N4O
Molecular Weight: 366.50
Purity :NSI-189 has a purity not less than 99%.
NSI-189 Describtion :
NSI-189 is a benzylphiperizine-aminiopyridine, nootropic and neurogenic research chemical created by Neuralstem, Inc. that was derived from pyrazine and nicotinamide. Studies have shown that it stimulates neurogenesis of human hippocampus-derived neural stem cells in vivo and vitro . In healthy adult mice, NSI-189 has been shown to increase the hippocampal volume by 20% and reverse behavioral symptoms in mouse depression models, meaning at the source it could address depression . The hippocampus is responsible for spatial navigation, along with the consolidation of information from short-term memory to long-term memory.
The chemical entity stimulates new neuron growth in the hippocampus, which is an area of the brain that is believed to be contributory in conditions such as post-traumatic stress disorder (PTSD), Alzheimers disease, and major depressive disorder (MDD).
NSI-189s Method of Action:
Although it has been demonstrated in rats and chimps, the suggestion that having too small of a hippocampus causes depression and other diseases in humans is still technically just a theory. NSI-189 increases hippocampal volume in adult mice by 20%, a region of the brain that is one of the first to suffer damage resulting in memory loss, disorientation, encephalitis, and hypoxia from diseases such as Alzheimers .
Nsi-189 Effect
1) Enhance cognition and memory formation.
2) Anxiolytic properties.
3) Anti-depressive effect .
4) Treatment of Alzheimers and Parkinsons disease.
5) Increase coordination.
6) Improves mood.
7) Help fight fatigue.
8) Prevent oxidation within the brain.
9) Treat alcohol related brain damage.
COA
Product name |
NSI-189 |
||
CAS No. | -40-3 |
Outer Packing | |
Production date | Dec. 15. 2016. |
Shelf life | Dec. 14th. 2019 |
Standard adopted | in-house standard |
||
Items of analysis | Specification | Results | |
Appearance |
Off-white powder |
Confrom |
|
Identification |
IR and HPLC spectrum shall conform to the standard sample |
conform |
|
Melting Point |
83ºC~86ºC |
84.3ºC~85.6ºC |
|
Loss on Drying |
Less than 0.5% |
0.29% |
|
Purity(On Dried Base,HPLC) |
NLT 99.5 % |
99.62% |
|
Total Impurity |
Less than 0.5% |
0.33% |
|
Residue On Ignition |
≤0.2% |
0.16% |
|
Heavy metal |
≤20ppm |
conform |
|
Conclusion |
Qualified |
Our adwantage:
1, High quality with competitive price:
1) Standard: Enterprise Standard
2) All Purity≥98%
3) We are manufacturer and can provide high quality products with factory price.
2, Fast and safe delivery
1) Parcel can be sent out within 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
3, We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customerss requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
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