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Home>Products>Raw Steroid Powders>99% Purity Aldactone CAS 52-01-7 Spironolactones for Urinary Infection Treatment

99% Purity Aldactone CAS 52-01-7 Spironolactones for Urinary Infection Treatment
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52-01-7
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zhuhai Tianhui Chemical Co.,Ltd.2020-07-10 09:46:19
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Product Details
Name: | Spironolactones | Appearance: | white powder | Purity: | 99% |
Product Description
99% Purity Aldactone CAS 52-01-7 Spironolactones for Urinary Infection Treatment
Quick Details:
- Spironolactone
- Alias: Aldactone;Antisterone;spirolactone
- CAS NO: 52-1-7
- Einecs No: 200-133-6
- MF: C24H32O4SMW: 416.58
- Purity: 98.0%
- Grade: Pharmaceutical Grade
- Manufacturer : Hezhong
- Appearance: White or white crystal powder of fine;Slightly bitter taste, odourless or slightly mercaptan odor.Insoluble in water, soluble in ethanol, soluble in benzene or ethyl acetate.
- Usage: Spironolactone is competitive inhibition of aldosterone drugs, drug itself is not active, role is diuresis and endogenous competitive aldosterone antagonist and happen, belongs to the potassium diuretics.
Description:
Spironolactone (INN, BAN, USAN) commonly referred to simply as spiro, and marketed primarily under the brand name Aldactone in most countries, is a synthetic, steroidal antimineralocorticoid and antiandrogen that also has some weak progestogen properties, as well as some indirect estrogen and glucocorticoid effects. It is used primarily as a diuretic and antihypertensive, but may also be employed for the purpose of reducing elevated or unwanted androgen activity in the body. It acts predominantly as an antagonist of the mineralocorticoid (or aldosterone) and androgen receptors, and in relation to its antimineralocorticoid effects, belongs to a class of pharmaceutical drugs known as potassium-sparing diuretics.
Spironolactone is a relatively old drug, having been introduced clinically in 1959. Futterman and Lemberg have predicted that spironolactone will be less commonly used in cardiovascular conditions (e.g., heart failure and hypertension) as the newer agents like the structurally-related compound eplerenone (also an aldosterone antagonist) are more selective and lack many of the side effects and actions of spironolactone that are undesirable in that particular patient population. However, spironolactone remains more widely used as an antiandrogen than eplerenone for patients in whom this effect is a main goal.
It is on the World Health Organizations List of Essential Medicines, a list of the most important medication needed in a basic health system.
Application :
Spironolactone is used primarily to treat heart failure, edematous conditions such as nephrotic syndrome or ascites in patients with liver disease, essential hypertension, hypokalemia, secondary hyperaldosteronism (such as occurs with hepatic cirrhosis), and Conns syndrome (primary hyperaldosteronism). On its own.
Because spironolactone reduces the bodys production of testosterone and blocks the androgen receptors, it can cause effects associated with low testosterone levels and hypogonadism in males. For this reason, men are typically not prescribed spironolactone for any longer than a short period of time, e.g. for an acute exacerbation of heart failure. The newer drug, eplerenone has been approved by the U.S. Food and Drug Administration for treatment of heart failure, but lacks the rather potent antiandrogen effects and thus is far more suitable for men for whom long term medication is being chosen. Unlike with some other diuretics, potassium supplementation should not be administered while taking spironolactone as this may cause dangerous elevations in serum potassium levels resulting in hyperkalemia and potentially deadly cardiac arrythmias. Physicians must be careful to monitor potassium levels in both males and females who are taking spironolactone, especially during the first twelve months of use and whenever the dosage is increased.
Packaging & Delivery:
We have sufficient stock and can delivery promptly at the very day when receive the payment. The Sophisticated and professional logistic agent will coordinate with us to provide our customers with fast delivery and secure shipping. We also have well-trained and disciplined packing team. 10 grams to 100kg powders will be shipped at one time to your destination in unique ways. It will be arranged in fast and discreet shipment for customs pass Guaranteed. At the same time, packing pictures and tacking code will be provided within 12 hours after receiving the payment. Updated tracking information will be provided every other day. We pay much attention to after-sale service: Any questions or problems after receiving the product, please feel free to contact us. Problems would be solved immediately.
Competitive Advantages:
- High quality and good price.
- Delivey in time.
- 100% customs pass guaranteed.
- Good after-sale service. Solve your problems in time
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